EBOO stands for Extracorporeal Blood Oxygenation and Ozonation, often called the most advanced form of ozone therapy. Blood is drawn from one arm, passed through a closed-loop external filtration system where it is exposed to a medical-grade ozone/oxygen mixture, and returned through the other arm. Unlike simpler ozone therapies, EBOO adds a filtration step that physically removes toxins, inflammatory debris, and oxidized waste, returning cleaner, oxygen-enriched blood to the body.

Tijuana clinics market EBOO for chronic and hard-to-treat conditions, including autoimmune diseases (Hashimoto's, lupus, rheumatoid arthritis, MS), Lyme disease, long COVID and post-viral recovery, chronic fatigue, fibromyalgia, Epstein-Barr, chronic infections, neurodegenerative conditions, and heavy-metal or mold toxicity. It is also offered as supportive care during cancer treatment and is promoted for immune support, detoxification, and general longevity and wellness.

Mexican clinics generally advertise lower per-session pricing than clinics in the United States, where a single session runs roughly $700–$1500 (packages of three or more sessions typically receive a 20–30% discount). Most Tijuana clinics do not post fixed prices publicly and ask patients to request a personalized quote. Keep in mind that advertised savings in Mexico can shrink once travel, lodging, and time away from work are factored in.

A single session typically lasts about 45–60 minutes with no required downtime. Providers usually recommend an initial series of about 3–6 sessions spaced one to two weeks apart, followed by maintenance sessions individualized to how each patient responds.

Clinics describe EBOO as safe when performed under physician supervision in a sterile setting using a closed-loop system to protect the blood. Reported side effects are said to be rare and mild — temporary fatigue or light-headedness that usually resolves within 24 hours. Worth knowing: EBOO is not FDA-approved for these uses, which is part of why it is offered in Mexico, and independent clinical evidence for many of the marketed benefits remains limited.

Tijuana has become a leading medical-tourism destination because therapies like EBOO are available there without the regulatory restrictions found in the United States, often at lower advertised prices, and just across the border for patients from the U.S. and Canada. Clinics emphasize accessibility, modern equipment, and treatment of conditions where conventional options have been exhausted.